Celiac Disease: Symptoms & How It's Treated | SPARSH Hospital

Published in : Gastroenterology | February 6, 2025 |

Celiac Disease: Symptoms & How It's Treated

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Celiac disease is an autoimmune disorder where the ingestion of gluten damages the small intestine. Symptoms include digestive issues, fatigue, and nutrient deficiencies. It is managed through a strict gluten-free diet, and early diagnosis is vital to prevent complications.

What is Celiac Disease?

Celiac disease is a chronic autoimmune disorder in which consuming gluten—a protein found in wheat, barley, and rye—triggers an immune response that damages the small intestine. Over time, this impairs the body’s ability to absorb essential nutrients, leading to a variety of health issues. While anyone can develop celiac disease, it often runs in families and is more common in people with other autoimmune conditions.

Celiac Disease Symptoms

The symptoms of celiac disease can vary widely, affecting both the digestive system and other parts of the body. Common celiac disease symptoms include:

Digestive Symptoms

  • Abdominal Pain and Bloating

Many individuals with celiac disease experience discomfort and swelling in the abdominal region, often accompanied by excessive gas. This occurs as gluten triggers inflammation in the small intestine, leading to irritation and discomfort.

  • Chronic Diarrhoea

Persistent loose stools with a foul smell are a hallmark symptom. This results from the small intestine’s inability to properly absorb nutrients, causing undigested food to pass quickly through the digestive system.

  • Constipation

While diarrhoea is common, some individuals experience difficulty passing stools due to inflammation that disrupts normal gut function. Constipation can alternate with bouts of diarrhoea in some cases.

Non-Digestive Symptoms

  • Fatigue

Nutrient deficiencies, particularly iron, result in persistent tiredness and low energy levels. The body struggles to function optimally due to the lack of essential nutrients.

Despite a regular diet, unexplained weight loss can occur as the damaged intestinal lining fails to absorb adequate nutrients, leading to malnutrition.

  • Skin Rash (Dermatitis Herpetiformis)

This itchy, blistering rash is a less common symptom but directly linked to celiac disease. It often appears on the elbows, knees, or scalp and resolves with a gluten-free diet.

  • Bone and Joint Pain

Calcium and vitamin D deficiencies, caused by poor nutrient absorption, can lead to weakened bones and discomfort in joints. Prolonged deficiencies may increase the risk of osteoporosis.

In children, additional symptoms such as delayed growth, short stature, and behavioural issues may appear.

What Causes Celiac Disease?

The causes of celiac disease are linked to a combination of genetic predisposition and environmental factors:

  • Genetics: Certain gene variations (HLA-DQ2 and HLA-DQ8) increase susceptibility.
  • Gluten exposure: Consumption of gluten-containing foods triggers the immune response.
  • Infections: Early life infections may activate the disease in genetically predisposed individuals.
  • Gut microbiota: An imbalance in gut bacteria might influence disease onset.

Celiac Disease Diagnosis

A proper celiac disease diagnosis involves a combination of medical history, physical exams, and specific tests:

Celiac Disease Test Options

  • Blood Tests: Serological tests look for antibodies like tTG-IgA, which indicate an immune response to gluten.
  • Endoscopy and Biopsy: A small sample of the small intestine is taken to confirm intestinal damage.
  • Genetic Testing: Detects HLA-DQ2 or HLA-DQ8 genes, though their presence alone doesn’t confirm the disease.

It is crucial not to start a gluten-free diet before testing, as this may interfere with diagnostic accuracy.

Celiac Disease Treatments

The primary celiac disease treatment is dietary management:

Gluten-Free Diet

  • Complete avoidance of gluten-containing grains (wheat, rye, barley).
  • Cross-contamination awareness: Ensure food isn’t contaminated during preparation.

Nutritional Support

  • Supplements: Address deficiencies in iron, calcium, vitamin D, and folate.
  • Dietitian guidance: A dietitian can help design a balanced gluten-free diet.

Medication

While there is no medication to cure celiac disease, ongoing research is exploring treatments to block gluten’s effects on the intestine.

Managing Complications

  • Bone health monitoring: For osteoporosis risk.
  • Treatment for dermatitis herpetiformis: Dapsone is often prescribed to manage the rash.

When to See a Doctor?

If you or a family member experiences persistent digestive issues, fatigue, or unexplained weight loss, it’s time to consult a specialist. Please visit SPARSH for gastroenterologists in Bangalore. Here you can expect comprehensive care, from accurate diagnosis to personalised treatment plans. Early intervention can prevent complications such as malabsorption or osteoporosis.

Conclusion

Celiac disease is a lifelong condition that requires strict dietary adherence to manage symptoms and prevent complications. Early detection through appropriate testing and maintaining a gluten-free diet are critical steps in achieving a good quality of life. If you suspect symptoms or have a family history of celiac disease, seek professional guidance promptly.

Frequently Asked Questions

What is the best way to manage celiac disease?

The best approach to managing celiac disease involves a lifelong commitment to a gluten-free diet. This means avoiding all foods that contain wheat, barley, or rye. Additionally, working with a dietitian can help address nutritional deficiencies by ensuring the inclusion of essential nutrients like iron, calcium, and vitamin D. Regular follow-ups with a healthcare provider are crucial to monitor recovery and prevent complications.

Is celiac disease very serious?

Celiac disease is a serious condition if left untreated, as it can lead to complications such as malnutrition, osteoporosis, infertility, and even certain types of cancer. However, it is manageable with early diagnosis and adherence to a strict gluten-free diet. Timely treatment can significantly improve a patient’s quality of life and reduce the risk of long-term health issues.

What is stage 4 celiac disease?

Stage 4 celiac disease refers to the most severe level of intestinal damage, where the villi—tiny hair-like structures in the small intestine that absorb nutrients—are completely flattened. This results in significant malabsorption of essential nutrients, leading to symptoms like chronic diarrhoea, severe weight loss, and nutrient deficiencies. Medical intervention and dietary management are crucial at this stage to avoid further complications.

Can I live a normal life with celiac disease?

Yes, individuals with celiac disease can live a normal, healthy life if they strictly adhere to a gluten-free diet. Avoiding gluten not only alleviates symptoms but also helps in healing the intestinal lining and preventing complications. With proper dietary management and routine medical care, individuals can enjoy a fulfilling and active lifestyle.



Categories: Gastroenterology


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